%0 Case Reports %T Primary pleomorphic liposarcoma of the cecum case report. %A Muiños AC %A Montes VG %A Carrasco JC %A Villanueva ÁFR %A García GDS %A Navarro EG %J Int J Surg Case Rep %V 121 %N 0 %D 2024 Aug 27 %M 38959610 暂无%R 10.1016/j.ijscr.2024.109961 %X BACKGROUND: The pleomorphic variant is the least common and consequently, the least known subtype of liposarcomas. It represents <5 % of all liposarcomas and develops during late adulthood.
METHODS: We report the case of a 77-year-old male who presented with pain in the right iliac fossa and right inguinal region. A CT scan revealed a stony lesion at the level of the cecum. A right hemicolectomy was performed, and the pathology report was positive for pleomorphic liposarcoma. Consequently, he was referred for adjuvant radiotherapy.
UNASSIGNED: Molecular analysis has validated the distinction of liposarcoma subtypes, although histological subtype remains the reliable prognostic parameter in daily practice, recent evidence suggests that genetic profiles may eventually influence risk stratification of individual patients.
CONCLUSIONS: The pleomorphic subtype of liposarcomas is infrequent, and they are very rare in the cecum, so it is currently recommended that patients be evaluated by a multidisciplinary team to make a therapeutic decision as it is a subtype of very aggressive behavior, before initiating any type of oncologic treatment.