%0 Journal Article
%T [A case of pleural metastasis of malignant peripheral nerve sheath tumor].
%A Huang MX
%A Tang P
%A Cen TT
%A Jia XT
%A Sun C
%A Jin J
%A Lai NY
%A Chen ZB
%A Ding QL
%A Tao FY
%A Ma HY
%J Zhonghua Jie He He Hu Xi Za Zhi
%V 47
%N 7
%D 2024 Jul 12
%M 38955752
暂无%R 10.3760/cma.j.cn112147-20240105-00011
%X Malignant peripheral nerve sheath tumor (MPNST) frequently metastasizes to the lungs, although pleural metastasis is rare. This article reported a case of pleural metastasis of MPNST. The patient was a young man who presented with 1 week of shortness of breath with dry cough. He had a history of malignant peripheral nerve sheath tumor. The patient was diagnosed with MPNST pleural metastasis after a thoracoscopic pleural biopsy, which revealed short spindle cell hyperplasia, immunohistochemical staining for S-100(+), SOX-10(+), Ki-67(+) with a positive index of 20%, and H3K27Me3(-) in the pleural pathology.<BR>恶性周围神经鞘膜瘤（malignant peripheral nerve sheath tumor，MPNST）常转移至肺，胸膜转移罕见。本文报道1例MPNST胸膜转移患者。患者青年男性，因“气促伴干咳1周”就诊。既往恶性周围神经鞘膜瘤病史。内科胸腔镜胸膜活检病理提示短梭形细胞增生，胸膜病理切片免疫组织化学染色S-100（+）、SOX-10（+）、Ki-67（+）阳性指数20%、H3K27Me3（-），诊断为MPNST胸膜转移。.