%0 Journal Article
%T Analysis of optical properties and response mechanism of H2S fluorescent probe based on rhodamine derivatives.
%A Sun G
%A Zhang RW
%A Chen XY
%A Chen YH
%A Zou LH
%A Zhang J
%A Li PG
%A Wang K
%A Hu ZG
%J Spectrochim Acta A Mol Biomol Spectrosc
%V 321
%N 0
%D 2024 Nov 15
%M 38955071
%F 4.831
%R 10.1016/j.saa.2024.124745
%X H2S plays a crucial role in numerous physiological and pathological processes. In this project, a new fluorescent probe, SG-H2S, for the detection of H2S, was developed by introducing the recognition group 2,4-dinitrophenyl ether. The combination of rhodamine derivatives can produce both colorimetric reactions and fluorescence reactions. Compared with the current H2S probes, the main advantages of SG-H2S are its wide pH range (5-9), fast response (30 min), and high selectivity in competitive species (including biological mercaptan). The probe SG-H2S has low cytotoxicity and has been successfully applied to imaging in MCF-7 cells, HeLa cells, and BALB/c nude mice. We hope that SG-H2S will provide a vital method for the field of biology.