%0 Journal Article %T Cell death in bryophytes: emerging models to study core regulatory modules and conserved pathways. %A Marchetti F %A Mariana Distéfano A %A Cainzos M %A Setzes N %A Cascallares M %A Alejandro López G %A Zabaleta E %A Carolina Pagnussat G %J Ann Bot %V 0 %N 0 %D 2024 Jul 2 %M 38953500 %F 5.04 %R 10.1093/aob/mcae081 %X Regulated cell death (RCD) plays key roles during essential processes along the plant life cycle. It takes part of specific developmental programs and maintains the organism homeostasis in response to unfavourable environments. Bryophytes could provide with valuable models to study developmental RCD processes as well as those triggered by biotic and abiotic stresses. Some pathways analogous to the ones present in angiosperms occur in the gametophytic haploid generation of bryophytes, allowing direct genetic studies. In this review, we focus on such RCD programs, identifying core conserved mechanisms and raising new key questions to analyse RCD from an evolutionary perspective.