%0 Journal Article
%T Microneedle-mediated drug delivery for neurological diseases.
%A Tan S
%A Wang Y
%A Wei X
%A Xiao X
%A Gao L
%J Int J Pharm
%V 661
%N 0
%D 2024 Aug 15
%M 38950662
%F 6.51
%R 10.1016/j.ijpharm.2024.124400
%X Neurological disorders, including brain injury, brain tumors, and neurodegenerative diseases, rank as the second leading cause of death worldwide. Exploring effective new treatments for neurological disorders has long been a hot research issue in clinical practice. Recently, microneedles (MNs) have attracted much attention due to their designation as a "painless and non-invasive" novel transdermal delivery method, characterized by their biocompatibility and sustainability. The advantages of MNs open an avenue for potential therapeutic interventions targeting neurological disorders. This review presents a concise overview of progress in the field of MNs, with highlights on the application in the treatment of neurological disorders. Notably, trends in the development of MNs and future challenges are also discussed.