%0 Journal Article
%T Retinal and Vitreous Changes Associated with Spontaneous Improvement in Myopic Macular Schisis.
%A Goudot M
%A Couturier A
%A Beaumont W
%A Gaudric A
%A Tadayoni R
%A Philippakis E
%J Ophthalmol Retina
%V 0
%N 0
%D 2024 Jun 29
%M 38950656
暂无%R 10.1016/j.oret.2024.06.017
%X <B>OBJECTIVE: </B>To describe the retinal and vitreous changes in eyes showing myopic macular schisis (MMS) improvement when vitrectomy was not performed and identify triggering factors.<BR><B>METHODS: </B>Retrospective observational study.<BR><B>METHODS: </B>Patients with nonoperated MMS.<BR><B>METHODS: </B>The records of patients with MMS who were followed without performing surgery for >6 months were retrospectively reviewed, and the eyes showing an anatomic improvement were included. Myopic macular schisis evolution was analyzed quantitatively (central foveal thickness [CFT], parafoveal thickness, maximum height) and qualitatively (presence/absence of foveal detachment, lamellar hole, epiretinal membrane, choroidal neovascularization, inner and outer retinoschisis, vitreous status) at baseline and at the final visit. An anatomic improvement was defined as a decrease in CFT by ≥50 μm.<BR><B>METHODS: </B>The rate of anatomic improvement of MMS without performing vitrectomy and the morphological changes observed in these cases.<BR><B>RESULTS: </B>In a cohort of 74 nonoperated eyes with MMS, MMS improved in 14 eyes (19%) after a mean follow-up of 55 ± 38 months (range, 8-138). In these improved cases, the mean decrease in CFT was 153 ± 166 μm (range, 24-635; P = 0.005) and a complete resolution of MMS was observed in 9 eyes (64%). In 9 eyes (64%), the improvement was associated with visible vitreous changes in the macular area on the OCT scans. The mean visual acuity, which was already good at baseline (20/50, 0.4 ± 0.2 logarithm of the minimum angle of resolution), increased at the last visit (20/40, 0.3 ± 0.3 logarithm of the minimum angle of resolution) but without reaching significance.<BR><B>CONCLUSIONS: </B>This long-term follow-up analysis showed that almost 20% of MMS in eyes without indication for surgery could improve over time. In most cases, the improvement was associated with an apparent resolution of vitreous tensions.<BR><B>BACKGROUND: </B>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.