%0 Journal Article
%T Adults With Spina Bifida Fare Worse than Young Adults: A Systemic Vulnerability in Urinary Tract Infection-Related Hospital Care.
%A Huen KH
%A Davis-Dao CA
%A Sayrs L
%A Ehwerhemuepha L
%A Martin-King C
%A Kain Z
%J J Urol
%V 0
%N 0
%D 2024 Jul 1
%M 38950379
%F 7.6
%R 10.1097/JU.0000000000004130
%X <B>UNASSIGNED: </B>We aim to estimate the odds of urinary tract infection (UTI)-related hospital care in spina bifida (SB) patients age 18 to 25 years as compared with patients with SB in adolescence (11-17 years) or adulthood (26-35 years). We hypothesize that patients with SB in the typical transitional age, 18 to 25 years, will have higher odds of UTI-related hospital care as compared to adolescent SB patients or adult SB patients.<BR><B>UNASSIGNED: </B>Using Cerner Real World Data, we performed a retrospective cohort analysis comparing SB patients to an age- and gender-matched controls. SB cases between 2015 and 2021 were identified and compared in 3 cohorts: 11 to 17 years (adolescents), 18 to 25 years (young adults [YA]), and 26 to 35 years (adults). Logistic regression analysis was used to characterize the odds of healthcare utilization.<BR><B>UNASSIGNED: </B>Of the 5497 patients with SB and 77,466 controls identified, 1839 SB patients (34%) and 3275 of controls (4.2%) had at least 1 UTI encounter. UTI-related encounters as a proportion of all encounters significantly increased with age in SB patients (adolescents 8%, YA 12%, adult 15%, P < .0001). Adjusting for race, sex, insurance and comorbidities, the odds of a UTI-related encounter in YA with SB was significantly higher than for adolescents with SB (adolescent OR = 0.65, 95% CI: 0.57-0.75, P < .001). YA had lower odds of a UTI-related encounter as compared with adults with SB (adult OR = 1.31, 95% CI: 1.16-1.49, P < .001).<BR><B>UNASSIGNED: </B>Young adults with SB have higher odds of UTI-related hospital care than adolescents, but lower odds of UTI-related hospital care when compared with adults.