%0 Journal Article %T FOXP3 snatches transcription factors depending on the context. %A Schmidleithner L %A Stüve P %A Feuerer M %J J Exp Med %V 221 %N 9 %D 2024 Sep 2 %M 38949640 %F 17.579 %R 10.1084/jem.20240940 %X FOXP3 hijacks DNA-binding proteins to regulate gene expression. In this issue of JEM, He et al. (https://doi.org/10.1084/jem.20232068) propose a dynamic model in which FOXP3 associates with DNA-binding proteins to regulate Treg cell function in response to environmental cues.