%0 Journal Article
%T Intradural cystic schwannomas of the spine: A case-based systematic review of an unusual tumor.
%A Terrapon APR
%A Stienen MN
%A Veeravagu A
%A Fehlings M
%A Bozinov O
%A Hejrati N
%J Brain Spine
%V 4
%N 0
%D 2024
%M 38947985
暂无%R 10.1016/j.bas.2024.102843
%X <B>UNASSIGNED: </B>Cystic schwannomas have only been reported in a few case reports/series. As a result, they may be misdiagnosed and a standardized management approach remains challenging to establish.<BR><B>UNASSIGNED: </B>The aim of this study was to compile all reported cases of cystic schwannomas and analyze the perioperative course based on a systematic review of the literature with an additional two cases from the authors' experience.<BR><B>UNASSIGNED: </B>We conducted a search of MEDLINE and CENTRAL databases for spinal intradural extramedullary cystic schwannomas, in accordance to the PRISMA statement. All title/abstracts were screened, and a full-text review of the remaining articles was conducted. The results were compiled in tables and summarized using means and standard deviation (SD), median and interquartile range, and percentage and 95% confidence intervals.<BR><B>UNASSIGNED: </B>We identified 263 articles, of which 35, which reported 54 cases, were included. Including our case-reports (n = 56), patients had a mean age of 47.7 years (SD ± 13.0 years) at presentation, 57% were males, and most lesions were lumbar (43%). The most common symptoms were pain (82%) and muscle weakness (68%) with 84% of patients showing neurological findings. 70% of patients showed a complete relief of symptoms after surgery and 96% reported improvement. Only four complications were reported.<BR><B>UNASSIGNED: </B>Schwannomas should be considered in the differential diagnosis of intradural extramedullary cystic lesions. Patients typically present with subacute to chronic pain and/or neurologic changes. Surgical resection is the primary therapeutic modality and usually has a good to excellent outcome.