%0 Journal Article
%T Diagnostic performance of EUS-guided tissue acquisition for solid pancreatic lesions ≤10 mm.
%A Kawasaki Y
%A Hijioka S
%A Nagashio Y
%A Ohba A
%A Maruki Y
%A Takeshita K
%A Takasaki T
%A Agarie D
%A Hagiwara Y
%A Hara H
%A Okamoto K
%A Yamashige D
%A Kondo S
%A Morizane C
%A Ueno H
%A Mizui T
%A Takamoto T
%A Nara S
%A Ban D
%A Esaki M
%A Saito Y
%A Hiraoka N
%A Okusaka T
%J Endosc Ultrasound
%V 13
%N 2
%D 2024 Mar-Apr
%M 38947747
%F 5.275
%R 10.1097/eus.0000000000000052
%X <B>UNASSIGNED: </B>EUS tissue acquisition (EUS-TA) is the standard diagnostic method for solid pancreatic lesions (SPLs); however, there are few reports on EUS-TA results for SPLs ≤10 mm. Furthermore, given the recent advent of fine-needle biopsy, the current diagnostic accuracy of EUS-TA for SPLs ≤10 mm is unknown. This study aimed to evaluate the diagnostic accuracy and efficacy of EUS-TA for SPLs ≤10 mm.<BR><B>UNASSIGNED: </B>We retrospectively analyzed the data of 109 patients with SPLs ≤10 mm who underwent EUS-TA. All patients underwent rapid on-site specimen evaluation.<BR><B>UNASSIGNED: </B>The median tumor diameter was 8 mm (range, 2.5-10 mm), and the technical success rate was 99.1% (108/109). Adverse events were observed in 3 patients (2.8%). The diagnostic performance was as follows: sensitivity, 90.1% (64/71); specificity, 97.3% (36/37); accuracy, 92.6% (100/108); positive predictive value, 98.5% (64/65); and negative predictive value, 83.7% (36/43). Multivariate analysis revealed that the number of punctures (odds ratio, 7.03; 95% confidence interval, 1.32-37.5; P = 0.023) and tumor type (odds ratio, 11.90; 95% confidence interval, 1.38-102.0; P = 0.024) were independent risk factors for inaccurate EUS-TA results. The diagnostic accuracy of EUS-TA for pancreatic ductal adenocarcinoma was 87.5% (14/16). No EUS-TA-related needle-tract seeding was observed in patients with pancreatic ductal adenocarcinoma during the observation period.<BR><B>UNASSIGNED: </B>EUS-TA for SPLs ≤10 mm showed adequate diagnostic accuracy and was safe for use with rapid on-site specimen evaluation in all cases.