%0 Journal Article
%T The pressing need for study on the effects of Mpox on the progression of vascular inflammation: A well-timed call.
%A Meem SS
%A Proma AY
%A Bhuiyan MA
%A Dewan SMR
%J Health Sci Rep
%V 7
%N 7
%D 2024 Jul
%M 38946778
暂无%R 10.1002/hsr2.2223
%X <B>UNASSIGNED: </B>This article explored the possibility that the Mpox virus (MPXV) may initiate or stimulate the consequences of vascular inflammation. In 1970, it was discovered that Macaca cynomolgus primates infected with MPXV also infected humans in the Democratic Republic of the Congo.<BR><B>UNASSIGNED: </B>The study demonstrates that MPXV invades host cells via viral proteins and surface receptors, initiating the release of diverse inflammatory mediators such as IL-1, IL-6, TNF-α, CCL2, CXCL2, CXCL8, CXCL10, and so forth probably through endothelial dysfunction by reactive oxygen species production. In general, these mediators have been found to contribute to vascular inflammation and the formation of atherosclerotic plaque at a later stage, which may contribute to the onset of vascular inflammation.<BR><B>UNASSIGNED: </B>The discussed association between vascular inflammation and Mpox has the potential to be an important finding in the field of vascular biology research.