%0 Journal Article
%T Marital History and Cognition in a Chinese Longevity Cohort.
%A Huang X
%A Hilal S
%J J Alzheimers Dis
%V 0
%N 0
%D 2024 Jun 22
%M 38943391
%F 4.16
%R 10.3233/JAD-240176
%X <B>UNASSIGNED: </B>Marital factor has been associated with dementia and Alzheimer's disease, but there is limited evidence on the impact of holistic marital history over time.<BR><B>UNASSIGNED: </B>This study aimed to examine association of marital history with cognition.<BR><B>UNASSIGNED: </B>The study included 24,596 dementia-free participants from the Chinese Longitudinal Healthy Longevity Study (CLHLS). Holistic marital history was collected at baseline, categorizing participants into five groups: widow-single, widow-remarried, divorce-single, divorce-remarried and married based on the first two marriages. Dementia was collected at follow-up through self-report or from a delegate if the participant was deceased. For 15,355 participants, the Chinese Mini-Mental Status Examination (CMMSE) was administered at both baseline and follow-ups. Cognitive impairment was defined as a follow-up CMMSE score below 18, and rate of cognitive change was calculated as the change in CMMSE score between consecutive visits divided by the duration.<BR><B>UNASSIGNED: </B>Compared with married older adults, widow-single group had significantly higher risk of dementia (HR 1.28, 95% CI 1.05, 1.54), cognitive impairment (HR 1.31, 95% CI 1.17, 1.47) and significantly faster decline of MMSE score (β -0.09, 95% CI -0.17, -0.01). Meanwhile, widow-remarried group had significantly lower risk of dementia, cognitive impairment and slower MMSE score decline than widow-single group, although the differences were only significant among female but not male.<BR><B>UNASSIGNED: </B>In this prospective cohort, married older adults and those widowed but with a second marriage had significantly better cognition than widowed individuals who did not remarry.