%0 Journal Article
%T Extreme overall mushroom genome expansion in Mycena s.s. irrespective of plant hosts or substrate specializations.
%A Harder CB
%A Miyauchi S
%A Virágh M
%A Kuo A
%A Thoen E
%A Andreopoulos B
%A Lu D
%A Skrede I
%A Drula E
%A Henrissat B
%A Morin E
%A Kohler A
%A Barry K
%A LaButti K
%A Salamov A
%A Lipzen A
%A Merényi Z
%A Hegedüs B
%A Baldrian P
%A Stursova M
%A Weitz H
%A Taylor A
%A Koriabine M
%A Savage E
%A Grigoriev IV
%A Nagy LG
%A Martin F
%A Kauserud H
%J Cell Genom
%V 0
%N 0
%D 2024 Jun 19
%M 38942024
暂无%R 10.1016/j.xgen.2024.100586
%X Mycena s.s. is a ubiquitous mushroom genus whose members degrade multiple dead plant substrates and opportunistically invade living plant roots. Having sequenced the nuclear genomes of 24 Mycena species, we find them to defy the expected patterns for fungi based on both their traditionally perceived saprotrophic ecology and substrate specializations. Mycena displayed massive genome expansions overall affecting all gene families, driven by novel gene family emergence, gene duplications, enlarged secretomes encoding polysaccharide degradation enzymes, transposable element (TE) proliferation, and horizontal gene transfers. Mainly due to TE proliferation, Arctic Mycena species display genomes of up to 502 Mbp (2-8× the temperate Mycena), the largest among mushroom-forming Agaricomycetes, indicating a possible evolutionary convergence to genomic expansions sometimes seen in Arctic plants. Overall, Mycena show highly unusual, varied mosaic-like genomic structures adaptable to multiple lifestyles, providing genomic illustration for the growing realization that fungal niche adaptations can be far more fluid than traditionally believed.