%0 Case Reports %T Unusual presentation of metastatic melanoma. %A La A %A Asarian A %A Xiao P %J J Surg Case Rep %V 2024 %N 6 %D 2024 Jun %M 38933829 暂无%R 10.1093/jscr/rjae429 %X Urinary bladder with concurrent colonic melanoma is an exceptionally uncommon occurrence, posing a diagnostic challenge for clinicians. While rare, it warrants consideration as a potential differential diagnosis, particularly in patients without a history of melanoma who present with persistent hematuria due to its aggressive nature. We present a case of a 55-year-old female with malignant melanoma involving the colon and urinary bladder presenting with hematuria. Given the scarcity of cases and variability in clinical management approaches, there is a pressing need for research efforts to establish standardized protocols and conduct trials to guide clinical practice in this rare entity.