%0 Journal Article
%T [Research progress on the mechanisms of probiotics promoting wound healing].
%A Dong J
%A Wang X
%A Bai G
%A Wang D
%J Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
%V 41
%N 3
%D 2024 Jun 25
%M 38932552
暂无%R 10.7507/1001-5515.202208003
%X Slow wound healing has been a troublesome problem in clinic. In China, traditional methods such as antibiotics and silver sulfadiazine are used to treat skin wound, but the abuse use has many disadvantages, such as chronic wounds and pathogen resistance. Studies have shown that the microorganisms with symbiotic relationship with organisms have benefits on skin wound. Therefore, the way to develop and utilize probiotics to promote wound healing has become a new research direction. In this paper, we reviewed the studies on the bacteriotherapy in the world, described how the probiotics can play a role in promoting wound healing through local wound and intestine, and introduced some mature probiotics products and clinical trials, aiming to provide foundations for further development of bacteriotherapy and products.<BR>伤口愈合缓慢是目前临床上较为棘手的问题，国内多采用抗生素和磺胺嘧啶银等较为传统的方法来治疗皮肤伤口，但其不恰当的使用存在诸多弊端，如导致伤口的慢性化和病原体的耐药性等。有研究表明，与机体存在共生关系的微生物可对皮肤伤口产生有益影响，因此如何开发并利用益生菌来促进伤口愈合已然成为了一项新的研究方向。本文根据国内外有关益生菌疗法的相关文献，阐述了益生菌是如何通过局部伤口和肠道来发挥其促愈合作用的，并且还提到了部分相对成熟的益生菌产品和临床试验，旨在为国内进一步开展益生菌疗法及其产品研发提供相关依据。.