%0 Journal Article %T Cost and Cost-Effectiveness of the Mediterranean Diet: An Update of a Systematic Review. %A Colaprico C %A Crispini D %A Rocchi I %A Kibi S %A De Giusti M %A La Torre G %J Nutrients %V 16 %N 12 %D 2024 Jun 16 %M 38931254 %F 6.706 %R 10.3390/nu16121899 %X It is well known that the Mediterranean diet (DM) is beneficial for health, as years of research globally have confirmed. The aim of this study was to update a previous systematic review that assessed the cost-effectiveness of adherence to the DM as a strategy for the prevention of degenerative diseases by evaluating the economic performance of this diet. The research approach utilized three electronic databases: PubMed, Scopus, and Web of Science. A comprehensive search was conducted to retrieve articles based on a PRISMA-compliant protocol registered in PROSPERO: CRD 42023493562. Data extraction and analysis were performed on all included studies. One thousand two hundred and eighty-two articles were retrieved, and once duplicates and irrelevant articles were removed, fifteen useful articles were reviewed. The studies indicated a clear link between dietary habits, health, and economic aspects related to dietary cost and health spending. Recognizing the significant health benefits associated with adopting DM and the potential savings on health care spending, it is important for national public health programs to consider policies that support this lifestyle.