%0 Journal Article
%T REM and NREM Sleep Parasomnia in Anti-NMDA Receptor Encephalitis.
%A Ribeiro L
%A Psimaras D
%A Vollhardt R
%A Honnorat J
%A Méneret A
%A Demeret S
%A Celier A
%A Valyraki NE
%A Cousyn L
%A Le Guennec L
%A Arnulf I
%A Gales AZ
%J Neurol Neuroimmunol Neuroinflamm
%V 11
%N 5
%D 2024 Sep
%M 38917379
%F 11.36
%R 10.1212/NXI.0000000000200203
%X OBJECTIVE: Encephalitis with anti-N-methyl-d-aspartate receptor antibodies (anti-NMDARe) is a rare disorder characterized by cognitive impairment, psychosis, seizures, and abnormal movements. Abnormal behaviors during REM sleep have not been described in anti-NMDARe.
METHODS: Patients were monitored by video-polysomnography on a first night followed by multiple sleep latency tests and 18 hours of bed rest.
RESULTS: Two patients with anti-NMDARe developed during the acute and postacute phase parasomnias including REM sleep behavior disorder and continuous finalistic quiet gesturing during a mixed N2/R sleep. The parasomnia disorder was improved by gabapentin and clonazepam.
CONCLUSIONS: Video-polysomnography avoids misdiagnosing these parasomnia behaviors for seizure or movement disorders and allows adequate treatment.