%0 Journal Article
%T Congenital Generalized Lipodystrophy in a Division 1 Female Sprinter.
%A Schleich KT
%A Novakofski KD
%A Thomsen TW
%A Woodroffe L
%A Slayman TG
%J Clin J Sport Med
%V 34
%N 4
%D 2024 Jul 1
%M 38914100
%F 3.454
%R 10.1097/JSM.0000000000001214
%X <B>UNASSIGNED: </B>A 21-year-old African American Division 1 female sprinter presented with 3-weeks history of right great toe and forefoot pain, fatigue, and a 30-day continuous menstrual cycle despite implanted etonogestrel (Nexplanon) inserted 3 years prior. An magnetic resonance imagine (MRI) identified likely stress fracture of the second metatarsal base with a diffusely low T1 signal indicating hyperactive red marrow. Due to persistent pain, a follow-up MRI was ordered 6 months later and indicated serous atrophy of the bone marrow, prompting a further metabolic workup notable for triglycerides exceeding 4000 mg/dL and a hemoglobin A1c of 10.9%. This case highlights the manifestation of a rare congenital lipodystrophy that initially presented as a relatively classic stress fracture and metrorrhagia in a female athlete.