%0 Journal Article
%T Lipid-Based Nanoparticles for RNA Delivery.
%A Calderón-Colón X
%A Egan R
%J Methods Mol Biol
%V 2822
%N 0
%D 2024
%M 38907931
暂无%R 10.1007/978-1-0716-3918-4_25
%X Various nanoparticle-based delivery systems have been developed for the encapsulation and protection of active cargoes. Lipid nanoparticles represent one of the most widely used nanoparticle-based delivery systems for in vitro and in vivo applications, especially for the delivery of ribonucleic acid (RNA). In this chapter, a simple bulk mixing method for the encapsulation of RNA is described along with characterization techniques for measuring encapsulation efficiency and nanoparticle physicochemical properties.