%0 Journal Article %T Overcoming colonialism in pathogen genomics. %A Saha S %A Hooda Y %A Malavige GN %A Nisar MI %J Lancet Digit Health %V 6 %N 7 %D 2024 Jul %M 38906617 %F 36.615 %R 10.1016/S2589-7500(24)00091-8 %X Historical legacies of colonialism affect the distribution and control of scientific knowledge today, including within the pathogen genomics field, which remains dominated by high-income countries (HICs). We discuss the imperatives for decolonising pathogen genomics, including the need for more equitable representation, collaboration, and capacity-strengthening, and the shared responsibilities that both low-income and middle-income countries (LMICs) and HICs have in this endeavour. By highlighting examples from LMICs, we illuminate the pathways and challenges that researchers in LMICs face in the bid to gain autonomy in this crucial domain. Recognising the inherent value of local expertise and resources, we argue for a more inclusive, globally collaborative approach to pathogen genomics. Such an approach not only fosters scientific growth and innovation, but also strengthens global health security by equipping all nations with the tools needed to respond to health crises.