%0 Case Reports %T A Rare Case of Metastatic Spiradenocarcinoma With CDKN2A Mutation. %A Trinh JQ %A Banskota SU %A Marr AS %J Oncology (Williston Park) %V 38 %N 6 %D 2024 06 10 %M 38899982 %F 2.533 %R 10.46883/2024.25921022 %X Spiradenocarcinomas are rare malignant skin adnexal tumors. We describe a novel case of a patient with an aggressive CDKN2A-mutated spiradenocarcinoma who responded to a CDK4/6 inhibitor. This case highlights the unique nature of spiradenocarcinomas as well as the potential benefit of targeted therapy.