%0 Journal Article
%T Burden of Long COVID-19 in a Cohort of Recovered COVID-19 Patients in Delhi, India.
%A Singh MM
%A Sharma H
%A Bhatnagar N
%A Borle AL
%A Rao S
%A Mishra S
%A Singh G
%A Singh T
%A Kapoor M
%A Kumar N
%J Cureus
%V 16
%N 5
%D 2024 May
%M 38899267
暂无%R 10.7759/cureus.60652
%X <B>BACKGROUND: </B>The long COVID phase is characterized by signs and symptoms persisting for at least three months after recovery from acute COVID-19 illness. There is limited data on comprehensive long-term clinical follow-up of COVID-19 patients.<BR><B>OBJECTIVE: </B>This study aims to explore the burden and symptomatology of long COVID syndrome and its association with various health parameters.<BR><B>METHODS: </B>This prospective observational study was conducted in Delhi from May 2022 to March 2023.<BR><B>METHODS: </B>A total of 553 adult patients who had recovered from COVID-19 were enrolled in the study. A sociodemographic and clinical profile was obtained using validated questionnaires, along with an evaluation of biochemical parameters to assess the associated factors.<BR><B>METHODS: </B>Chi-square test, unpaired t-test, and bivariate regression analysis were applied using Statistical Product and Service Solutions (SPSS, version 28; IBM SPSS Statistics for Windows, Armonk, NY). A p value of <0.05 was considered significant.<BR><B>RESULTS: </B>A total of 252 patients (45.6%) had long COVID syndrome, which was significantly associated with the presence of any pre-existing comorbidity (OR=1.46 (1.02-2.09); p=0.039), previous history of hypertension (OR=1.82 (1.07-3.09); p=0.027), and vaccination against COVID-19 (OR=1.392 (1.171-1.656); p=0.003). The most common symptoms reported were persistent fatigue (33.3%) and persistent dry cough (28.5%). Patients with long COVID syndrome are also reported to have poorer sleep quality. Biochemical findings showed abnormal T lymphocytes (9.3%) and raised HbA1c (11.9%).<BR><B>CONCLUSIONS: </B>Multiple risk factors and symptoms associated with long COVID syndrome were identified in this study. Research efforts and knowledge regarding the pattern of illness will aid in long-term monitoring and development of interventional strategies and guidelines for the care of recovered COVID-19 patients.