%0 Journal Article %T Ultrasound-Assisted and Ultrasound-Guided Thoracentesis: An Educational Review. %A Boccatonda A %A Baldini C %A Rampoldi D %A Romani G %A Corvino A %A Cocco G %A D'Ardes D %A Catalano O %A Vetrugno L %A Schiavone C %A Piscaglia F %A Serra C %J Diagnostics (Basel) %V 14 %N 11 %D 2024 May 29 %M 38893651 %F 3.992 %R 10.3390/diagnostics14111124 %X Thoracentesis is one of the most important invasive procedures in the clinical setting. Particularly, thoracentesis can be relevant in the evaluation of a new diagnosed pleural effusion, thus allowing for the collection of pleural fluid so that laboratory tests essential to establish a diagnosis can be performed. Furthermore, thoracentesis is a maneuver that can have therapeutic and palliative purposes. Historically, the procedure was performed based on a physical examination. In recent years, the role of ultrasound has been established as a valuable tool for assistance and guidance in the thoracentesis procedure. The use of ultrasound increases success rates and significantly reduces complications. The aim of this educational review is to provide a detailed and sequential examination of the procedure, focusing on the two main modalities, the ultrasound-assisted and ultrasound-guided form.