%0 Journal Article
%T Blood Substitutes with Gas Transfer Function.
%A Khromov AV
%A Novikov OO
%A Novikova EO
%J Bull Exp Biol Med
%V 176
%N 6
%D 2024 Apr 18
%M 38888647
%F 0.737
%R 10.1007/s10517-024-06094-z
%X The review presents the results of the blood substitute development based on perfluororganic compounds (PFC). The limitations of PFC due to which their further development was suspended are described. The presented data allows us to imagine a possible way to create optimal drugs based on PFC. Chemically inactive perfluorocomponents should be used - perfluorinated hydrocarbons and tertiary perfluorinated amines. However, in order to emulsify and stabilize the emulsion, other types of effective and chemically indifferent surfactants that do not interact with oxygen and other components of the drug are needed.