%0 Journal Article
%T A ratiometric fluorescent probe based on a novel fluorophore with high selectivity for imaging cysteine in living cells.
%A Miao Z
%A Li C
%A Pang S
%A Du C
%A Wei N
%A Zhang Y
%J Luminescence
%V 39
%N 6
%D 2024 Jun
%M 38881430
%F 2.613
%R 10.1002/bio.4806
%X As a biothiol, cysteine (Cys) is essential to both physiological and pathological processes and has been associated with many diseases, including neurological disorders, rheumatoid arthritis, and renal dysfunction. Therefore, the development of a high-performance probe for detecting Cys levels can help prevent and diagnose disease. In this study, a ratiometric fluorescent probe based on a novel fluorophore was developed for detecting Cys, and it showed high specificity and a rapid response time toward Cys. This probe demonstrates excellent biocompatibility and has been utilized effectively for the imaging of Cys in living cells.