%0 Case Reports %T Successful treatment of a lactating women with severe acne through the combination of fire needle and photodynamic therapy: A case report. %A Tang L %A Zhou X %A Su G %J Photodiagnosis Photodyn Ther %V 48 %N 0 %D 2024 Jun 6 %M 38848882 %F 3.577 %R 10.1016/j.pdpdt.2024.104234 %X Severe acne, characterized by cysts and nodules, can significantly impact a patient's self-image and quality of life [1]. In China, first-line treatments for severe acne typically include oral isotretinoin, topical benzoyl peroxide, and oral or topical antibiotics [2]. However, due to concerns about safety, oral isotretinoin and antibiotics are not recommended for lactating women, posing challenges in treating acne in this population and often leading to emotional distress. While photodynamic therapy has shown effectiveness in patients unwilling to take oral medications [3], treating severe acne during lactation remains a complex issue with limited research available. In this unique case, fire needle combined with photodynamic therapy was successfully utilized to address severe acne in a lactating patient. Following treatment, the patient experienced clearance of cysts, nodules, and pustules, as well as an improvement in depressive symptoms, yielding significant outcomes. Nevertheless, the efficacy and safety of this combined approach warrant further investigation through clinical trials.