%0 Journal Article %T HOW I DO IT: Cushing's disease-selective adenomectomy via an endoscopic transsphenoidal approach. %A Phillips N %A Nix P %A De Santos M %J Acta Neurochir (Wien) %V 166 %N 1 %D 2024 Jun 6 %M 38842720 %F 2.816 %R 10.1007/s00701-024-06078-y %X BACKGROUND: An ACTH-secreting pituitary adenoma is the most common cause of excessive endogenous glucocorticoid production resulting in Cushing's Syndrome. A multidisciplinary approach is paramount. Selective adenomectomy is the treatment of choice.
METHODS: Endoscopic transnasal transsphenoidal approach to the tumour, along with techniques for resection, are demonstrated.
CONCLUSIONS: Endoscopic transsphenoidal approaches with its magnified view of the pituitary gland allows precise microsurgical dissection during selective adenomectomy. This technique increases the possibility of proving a gross total resection, leading to clinical and biochemical cure in these patients.