%0 Journal Article
%T Ochrobactrum anthropi infection following corneal transplantation -a case report and review of literature.
%A Liu L
%A Wang C
%A Xu H
%A Hou L
%A Huang R
%A Shi X
%A Jia H
%J BMC Ophthalmol
%V 24
%N 1
%D 2024 Jun 3
%M 38831303
%F 2.086
%R 10.1186/s12886-024-03472-z
%X <B>BACKGROUND: </B>Ochrobactrum anthropi is widely distributed and primarily infects patients with compromised immune functions . Historically, O. anthropi has been considered to possess low toxicity and pathogenicity; however, recent studies suggest that it may in fact cause severe purulent infections. In this case study, we examine a case of O. anthropi infection following corneal transplantation, exploring the occurrence and outcomes of such post-operative infections.<BR><B>METHODS: </B>A retrospective analysis of cases involved examinations, genetic testing for diagnosis, and subsequent treatment. In patients undergoing partial penetrating keratoplasty with a fungal corneal ulcer perforation, anterior chamber exudation and purulence were observed post-surgery. Despite antifungal treatment, genetic testing of the anterior chamber fluid and purulent material confirmed O. anthropi infection. The use of antimicrobial treatment specifically targeting O. anthropi was found to be effective in treating the infection.<BR><B>CONCLUSIONS: </B>Inflammatory reactions following corneal transplantation should be should be monitored for the presence of other infections. Genetic testing has significant implications for clinical diagnosis and treatment.