%0 Journal Article
%T Interplay between male gonadal function and overall male health.
%A Asero V
%A Scornajenghi CM
%A Iaconis S
%A Sicignano E
%A Falcone A
%A Dinacci F
%A Pagano G
%A Carino D
%A Corvino R
%A Tresh A
%J J Basic Clin Physiol Pharmacol
%V 35
%N 3
%D 2024 May 1
%M 38830206
暂无%R 10.1515/jbcpp-2024-0054
%X The process-of-male reproduction is intricate, and various medical conditions-have the potential to disrupt spermatogenesis. Moreover, infertility in males can serve as an indicator of-potential future health issue. Numerous conditions with systemic implications have been identified, encompassing genetic factors (such as Klinefelter Syndrome), obesity, psychological stress, environmental factors, and others. Consequently, infertility assessment-presents an opportunity for comprehensive health counseling, extending-beyond discussions about reproductive goals. Furthermore, male infertility has been suggested as a harbinger of future health problems, as poor semen quality and a diagnosis of-male infertility are associated with an increased risk of hypogonadism, cardiometabolic disorders, cancer, and even mortality. This review explores the existing-literature on the relationship between systemic illnesses and male fertility, impacting both clinical-outcomes and semen parameters. The majority of the literature analyzed, which compared gonadal function with genetic, chronic, infectious or tumoral diseases, confirm the association between overall male health and infertility.