%0 Journal Article
%T Connectome-based schizophrenia prediction using structural connectivity - Deep Graph Neural Network(sc-DGNN).
%A Udayakumar P
%A Subhashini R
%J J Xray Sci Technol
%V 32
%N 4
%D 2024 May 29
%M 38820060
%F 2.442
%R 10.3233/XST-230426
%X <B>UNASSIGNED: </B>Connectome is understanding the complex organization of the human brain's structural and functional connectivity is essential for gaining insights into cognitive processes and disorders.<BR><B>UNASSIGNED: </B>To improve the prediction accuracy of brain disorder issues, the current study investigates dysconnected subnetworks and graph structures associated with schizophrenia.<BR><B>UNASSIGNED: </B>By using the proposed structural connectivity-deep graph neural network (sc-DGNN) model and compared with machine learning (ML) and deep learning (DL) models.This work attempts to focus on eighty-eight subjects of diffusion magnetic resonance imaging (dMRI), three classical ML, and five DL models.<BR><B>UNASSIGNED: </B>The structural connectivity-deep graph neural network (sc-DGNN) model is proposed to effectively predict dysconnectedness associated with schizophrenia and exhibits superior performance compared to traditional ML and DL (GNNs) methods in terms of accuracy, sensitivity, specificity, precision, F1-score, and Area under receiver operating characteristic (AUC).<BR><B>UNASSIGNED: </B>The classification task on schizophrenia using structural connectivity matrices and experimental results showed that linear discriminant analysis (LDA) performed 72% accuracy rate in ML models and sc-DGNN performed at a 93% accuracy rate in DL models to distinguish between schizophrenia and healthy patients.