%0 Journal Article %T Distribution of pufferfish saxitoxin- and tetrodotoxin-binding protein homolog and tetrodotoxin in the brain and pituitary of juvenile tiger puffer Takifugu rubripes. %A Amano M %A Amiya N %A Otsuka Y %A Homma J %A Hagio H %A Takatani T %A Yamamoto N %A Yamaguchi K %A Sakakura Y %J Toxicon %V 246 %N 0 %D 2024 Aug 2 %M 38810888 %F 3.035 %R 10.1016/j.toxicon.2024.107777 %X Pufferfish saxitoxin- and tetrodotoxin (TTX)-binding protein (PSTBP) is considered to transfer TTX between tissues. The immunohistochemical distribution of PSTBP-homolog (PSTBPh) and TTX in the brain and pituitary of hatchery-reared juvenile tiger puffer Takifugu rubripes was investigated. PSTBPh was observed mainly in the pars intermedia of the pituitary. TTX was only detected in a TTX-fed fish in the neurohypophysis of the pituitary and in several other brain regions. The relationship between PSTBPh and TTX is discussed.