%0 Journal Article
%T Evaluation of commercial immunodiffusion reagents for detecting serum anti-Paracoccidioides antibodies.
%A Cognialli RCR
%A Caceres DH
%A Telles FQ
%J Rev Soc Bras Med Trop
%V 57
%N 0
%D 2024
%M 38808801
%F 2.141
%R 10.1590/0037-8682-0094-2024
%X <B>BACKGROUND: </B>Accurate diagnosis of paracoccidioidomycosis is crucial for improving patient outcomes. Paracoccidioides antibody detection by double immunodiffusion (DID) is a convenient diagnostic tool, but testing performance can vary based on certain factors.<BR><B>METHODS: </B>We assessed DID performance using a commercially prepared Paracoccidioides reagents (IMMY, USA), involving 40 serum specimens, including 20 from patients with proven paracoccidioidomycosis and 20 from patients without the disease. The DID test demonstrated a sensitivity of 90% (95% CI=68%-99%) and a specificity of 100% (95% CI=83%-100%).<BR><B>CONCLUSIONS: </B>Our findings suggest that DID using commercial reagents may provide a feasible tool with satisfactory testing performance for anti-Paracoccidioides antibody detection.