%0 Journal Article
%T Advances in combined neuroendocrine carcinoma of lung cancer.
%A Han Z
%A Yang F
%A Wang F
%A Zheng H
%A Chen X
%A Meng H
%A Li F
%J Pathol Oncol Res
%V 30
%N 0
%D 2024
%M 38807858
%F 2.874
%R 10.3389/pore.2024.1611693
%X Lung cancer incidence and mortality rates are increasing worldwide, posing a significant public health challenge and an immense burden to affected families. Lung cancer encompasses distinct subtypes, namely, non-small-cell lung cancer (NSCLC) and small-cell lung cancer (SCLC). In clinical investigations, researchers have observed that neuroendocrine tumors can be classified into four types: typical carcinoid, atypical carcinoid, small-cell carcinoma, and large-cell neuroendocrine carcinoma based on their unique features. However, there exist combined forms of neuroendocrine cancer. This study focuses specifically on combined pulmonary carcinomas with a neuroendocrine component. In this comprehensive review article, the authors provide an overview of combined lung cancers and present two pathological images to visually depict these distinctive subtypes.