%0 Journal Article
%T Deciphering Unexpected Vascular Locations of Scedosporium spp. and Lomentospora prolificans Fungal Infections, France.
%A Vignals C
%A Emmerich J
%A Begueret H
%A Garcia-Hermoso D
%A Martin-Blondel G
%A Angoulvant A
%A Blez D
%A Bruneval P
%A Cassaing S
%A Catherinot E
%A Cahen P
%A Moluçon-Chabrot C
%A Chevenet C
%A Delhaes L
%A Escaut L
%A Faruch M
%A Grenouillet F
%A Larosa F
%A Limousin L
%A Longchampt E
%A Mellot F
%A Nourrisson C
%A Bougnoux ME
%A Lortholary O
%A Roux A
%A Rozenblum L
%A Puges M
%A Lanternier F
%A Bronnimann D
%J Emerg Infect Dis
%V 30
%N 6
%D 2024 Jun
%M 38781681
%F 16.126
%R 10.3201/eid3006.231409
%X Scedosporium spp. and Lomentospora prolificans are emerging non-Aspergillus filamentous fungi. The Scedosporiosis/lomentosporiosis Observational Study we previously conducted reported frequent fungal vascular involvement, including aortitis and peripheral arteritis. For this article, we reviewed 7 cases of Scedosporium spp. and L. prolificans arteritis from the Scedosporiosis/lomentosporiosis Observational Study and 13 cases from published literature. Underlying immunosuppression was reported in 70% (14/20) of case-patients, mainly those who had solid organ transplants (10/14). Osteoarticular localization of infection was observed in 50% (10/20) of cases; infections were frequently (7/10) contiguous with vascular infection sites. Scedosporium spp./Lomentospora prolificans infections were diagnosed in 9 of 20 patients ≈3 months after completing treatment for nonvascular scedosporiosis/lomentosporiosis. Aneurysms were found in 8/11 aortitis and 6/10 peripheral arteritis cases. Invasive fungal disease--related deaths were high (12/18 [67%]). The vascular tropism of Scedosporium spp. and L. prolificans indicates vascular imaging, such as computed tomography angiography, is needed to manage infections, especially for osteoarticular locations.