%0 Case Reports
%T Pyogenic liver abscess caused by an atypical hypervirulent Klebsiella pneumoniae K1-ST23 in Mexico.
%A Martínez-Hernandez L
%A Alvarado-Delgado A
%A Rodríguez-Medina N
%A Garcia-Peniche J
%A Donis-Hernández JJ
%A Perez-Rezendiz OA
%A Nava-Domínguez N
%A Duarte-Zambrano L
%A Tamayo-Legorreta EM
%A Garza-Ramos U
%J IDCases
%V 36
%N 0
%D 2024
%M 38779143
暂无%R 10.1016/j.idcr.2024.e01987
%X Hypervirulent K. pneumoniae infection has been raising worldwide and is one of the major causes of community-acquired pyogenic liver abscess. We described a case report of pyogenic liver abscess caused by an atypical hypervirulent (non-hypermucoviscous) K. pneumoniae K1 ST23 in a diabetic Asian patient who resided in Mexico. The susceptibility to antimicrobials, pathogenicity, molecular and genomic analysis were determined. A man from Guangdong (China) with a recent diagnosis of diabetes mellitus was admitted to the hospital, and he denied traveling in the last 3 months. A computed tomography revealed a right lobe liver abscess. On the third day after admission a Klebsiella pneumoniae isolate (14652) was obtained. The isolate corresponded to a susceptible K. pneumoniae with capsular type K1 and ST23 (CG23) and exhibited a non-hypermucoviscous phenotype. The isolate 14652 was genetically related to the globally distributed lineage ST23-KL1. This study describes the first case in Mexico of K. pneumoniae capsular type K1 and ST23 with an atypical hypervirulent phenotype.