%0 Case Reports %T Intensive Combination LDL-Lowering Therapy in a Patient With Homozygous Familial Hypercholesterolemia. %A Tada H %A Okada H %A Kawashiri MA %A Takamura M %J JACC Case Rep %V 29 %N 12 %D 2024 Jun 19 %M 38774638 暂无%R 10.1016/j.jaccas.2024.102367 %X We present a young boy with a diagnosis of homozygous familial hypercholesterolemia who presented with statin and ezetimibe resistance. The patient received lipoprotein apheresis at 6 years of age. His low-density lipoprotein cholesterol levels significantly were reduced by adding lomitapide and evinacumab, and his carotid plaque started to regress.