%0 Journal Article %T A hybrid CNN with transfer learning for skin cancer disease detection. %A Shukla MM %A Tripathi BK %A Dwivedi T %A Tripathi A %A Chaurasia BK %J Med Biol Eng Comput %V 0 %N 0 %D 2024 May 18 %M 38760598 %F 3.079 %R 10.1007/s11517-024-03115-x %X The leading cause of cancer-related deaths worldwide is skin cancer. Effective therapy depends on the early diagnosis of skin cancer through the precise classification of skin lesions. However, dermatologists may find it difficult and time-consuming to accurately classify skin lesions. The use of transfer learning to boost skin cancer classification model precision is a promising strategy. In this work, we proposed a hybrid CNN with a transfer learning model and a random forest classifier for skin cancer disease detection. To evaluate the efficacy of the proposed model, it was verified over two datasets of benign skin moles and malignant skin moles. The proposed model is able to classify images with an accuracy of up to 90.11%. The empirical results and analysis assure the feasibility and effectiveness of the proposed model for skin cancer classification.