%0 Journal Article
%T The Association Between Low Preoperative Phosphate Levels and Postliver Surgery Outcomes-A Single Center Experience.
%A Davis ES
%A Seda P
%A Kolodziej DT
%A Villa AT
%A Feng L
%A DiGioia O
%A Nayyar A
%A Jehan FS
%A Aziz H
%J J Surg Res
%V 299
%N 0
%D 2024 Jul 16
%M 38759329
%F 2.417
%R 10.1016/j.jss.2024.04.027
%X <B>BACKGROUND: </B>Previous research has demonstrated the impact of postoperative phosphate levels on liver regeneration and outcomes after liver resection surgeries, a potential predictor for regenerative success and liver failure. However, little is known about the association between low preoperative serum phosphate levels and outcomes in liver resections.<BR><B>METHODS: </B>We performed a retrospective analysis of liver resections performed at our institution. Patients were categorized based on preoperative phosphate levels (low versus normal). Our primary outcome measure was posthepatectomy liver failure.<BR><B>RESULTS: </B>A total of 265 cases met the study criteria. 71 patients (26.7%) had low preoperative phosphate levels. The incidence of posthepatectomy liver failure was higher in the low preoperative phosphate group (19.2% versus 12.4%). However, after propensity score matching, rates of posthepatectomy liver failure were similar between low and normal preoperative phosphate cohorts (13% versus 14%, P = 0.83).<BR><B>CONCLUSIONS: </B>Low preoperative phosphate levels were not associated with worse postoperative outcomes in this study. Further studies are warranted to investigate this association and its relevance as a clinical prognostic factor for postoperative liver failure.