%0 Case Reports %T Becoming Endemic: Anaplasmosis Imported Across State Borders. %A Abraham JD %A Wenning HS %A Saeed DA %A Derbarsegian A %A Brook BA %A He P %J Cureus %V 16 %N 4 %D 2024 Apr %M 38725788 暂无%R 10.7759/cureus.57902 %X Anaplasma phagocytophilum is the causative agent of human granulocytic anaplasmosis (HGA), a tick-borne illness with increasing incidence since being described in the 1990s. Importantly, the presentation can be vague, yet prompt treatment is paramount. An 81-year-old Caucasian female was hospitalized in Cincinnati, Ohio, for fever and confusion following prolonged outdoor exposure in Emlenton, Pennsylvania. She initially was treated for sepsis from presumed community-acquired pneumonia; however, the combination of leukopenia, thrombocytopenia, and elevated liver enzymes prompted empiric tick-borne illness consideration and treatment with rapid resolution in symptoms. Early recognition of HGA can reduce unnecessary treatments and improve patient outcomes.