%0 Journal Article
%T SVhawkeye: an ultra-fast software for user-friendly visualization of targeted structural fragments from BAM files.
%A Xiao Y
%A Yu T
%A Liang F
%A Hou T
%J Front Genet
%V 15
%N 0
%D 2024
%M 38721473
%F 4.772
%R 10.3389/fgene.2024.1352443
%X SVhawkeye is a novel visualization software created to rapidly extract essential structural information from third-generation sequencing data, such as data generated by PacBio or Oxford Nanopore Technologies. Its primary focus is on visualizing various structural variations commonly encountered in whole-genome sequencing (WGS) experiments, including deletions, insertions, duplications, inversions, and translocations. Additionally, SVhawkeye has the capability to display isoform structures obtained from iso-seq data and provides interval depth visualization for deducing local copy number variation (CNV). One noteworthy feature of SVhawkeye is its capacity to genotype structural variations, a critical function that enhances the accuracy of structural variant genotyping. SVhawkeye is an open-source software developed using Python and R languages, and it is freely accessible on GitHub (https://github.com/yywan0913/SVhawkeye).