%0 Case Reports
%T Pregnancy-associated atypical hemolytic uremic syndrome. Case report.
%A Barrera-Hoffmann C
%A Mariaca-Ortíz Y
%A Ruiz-Villa JG
%A Cuevas-Cruz LE
%A López-Mendoza MDR
%A Briones-Garduño JC
%J J Obstet Gynaecol Res
%V 50
%N 7
%D 2024 Jul 9
%M 38720638
%F 1.697
%R 10.1111/jog.15958
%X Pregnancy-associated atypical hemolytic uremic syndrome (P-aHUS) is a rare disease. There are only few reports in the literature, and most are in the puerperium period. It is a thrombotic microangiopathy (TMA) characterized for microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction. We report the case of a pregnant patient at 26.3 gestation weeks, who developed clinical features of TMA, neurological alterations, and septic shock; then after fetus and placental delivery, no clinical improvement was observed; a diagnostic protocol was performed due to suspicion of P-aHUS, showing improvement after the plasma exchange sessions and eculizumab. We present here a brief review of the case since it is an entity that needs to be suspected during pregnancy when TMA features and requires an immediate diagnosis to provide timely treatment.