%0 Case Reports
%T Statin-induced, immune-mediated necrotising myopathy triggered by malignancy successfully treated with immunosuppression.
%A Abouelazm A
%A Philops K
%A Amine A
%A Golam Y
%J Clin Med (Lond)
%V 24
%N 3
%D 2024 May 6
%M 38710328
%F 5.41
%R 10.1016/j.clinme.2024.100217
%X Statin-induced immune-mediated necrotising myopathy (IMNM) is an inflammatory myopathy that can present as proximal muscle weakness and, in some cases, as dysphagia and respiratory distress. In this report, we present a case of statin-induced IMNM in a 78-year-old male. The patient had significantly high levels of creatinine kinase and myoglobinuria and experienced gradual weakness in the proximal muscles for 1 month after initiating a 20 mg dose of Atorvastatin 10 months before admission. Rapid clinical improvement was observed with the use of high-dose glucocorticoids in conjunction with methotrexate.