%0 Case Reports
%T Anti-GBM disease in pregnancy.
%A Kafagi AH
%A Li AS
%A Jayne D
%A Brix SR
%J BMJ Case Rep
%V 17
%N 4
%D 2024 Apr 30
%M 38688578
暂无%R 10.1136/bcr-2023-257767
%X We present the case of a pregnant woman in her 20s who presented in her second trimester with severe pulmonary haemorrhage and dialysis-dependent acute kidney failure due to antiglomerular basement membrane (GBM) disease. Responding to therapy, she recovered kidney function and delivered a baby. During her pregnancy, she developed cytomegalovirus viraemia, gestational diabetes and pre-eclampsia. Here, we report the first combined use of cyclophosphamide, rituximab and intensified plasma exchange in anti-GBM disease in pregnancy, allowing minimal exposure to cytotoxic medication, resulting in live birth and dialysis independence.