%0 Journal Article
%T Protective Efficacy of Lyophilized Vesicular Stomatitis Virus-Based Vaccines in Animal Model.
%A Salawudeen A
%A Soule G
%A Tailor N
%A Klassen L
%A Audet J
%A Sloan A
%A Deschambault Y
%A Safronetz D
%J Emerg Infect Dis
%V 30
%N 5
%D 2024 May
%M 38666640
%F 16.126
%R 10.3201/eid3005.231248
%X We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus-based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicular stomatitis virus-based vaccines will each require extensive analysis to optimize stabilizing formulations.