%0 Case Reports
%T Guillain-Barre syndrome following scrub typhus: a case report and literature review.
%A Hu S
%A Lin Z
%A Liu T
%A Huang S
%A Liang H
%J BMC Neurol
%V 24
%N 1
%D 2024 Apr 25
%M 38664621
%F 2.903
%R 10.1186/s12883-024-03645-9
%X <B>BACKGROUND: </B>Scrub typhus is an acute infectious disease caused by Orientia tsutsugamushi. Guillain-Barre syndrome (GBS) is an autoimmune-mediated peripheral neuropathy with a frequent history of prodromal infections, but GBS associated with scrub typhus is very rare.<BR><B>METHODS: </B>We report a 51-year-old male patient who developed dysarthria and peripheral facial paralysis following the cure of scfrub typhus. CSF examination and electrophysiological findings suggested a diagnosis of GBS. After treatment with intravenous immunoglobulin, the patient's neurological condition improved rapidly.<BR><B>CONCLUSIONS: </B>Scrub typhus infection is likely to be a potential predisposing factor in GBS, while scrub typhus-associated GBS has a favorable prognosis.