%0 Journal Article
%T Driving pressure in mechanical ventilation: A review.
%A Zaidi SF
%A Shaikh A
%A Khan DA
%A Surani S
%A Ratnani I
%J World J Crit Care Med
%V 13
%N 1
%D 2024 Mar 9
%M 38633474
暂无%R 10.5492/wjccm.v13.i1.88385
%X Driving pressure (∆P) is a core therapeutic component of mechanical ventilation (MV). Varying levels of ∆P have been employed during MV depending on the type of underlying pathology and severity of injury. However, ∆P levels have also been shown to closely impact hard endpoints such as mortality. Considering this, conducting an in-depth review of ∆P as a unique, outcome-impacting therapeutic modality is extremely important. There is a need to understand the subtleties involved in making sure ∆P levels are optimized to enhance outcomes and minimize harm. We performed this narrative review to further explore the various uses of ∆P, the different parameters that can affect its use, and how outcomes vary in different patient populations at different pressure levels. To better utilize ∆P in MV-requiring patients, additional large-scale clinical studies are needed.