%0 English Abstract
%T [Hematological toxicities post-CAR-T cells: Recommendations of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
%A Alsuliman T
%A Aubrun C
%A Bay JO
%A Beguin Y
%A Bigenwald C
%A Brissot E
%A Chalandon Y
%A Chevallier P
%A Pagliuca S
%A Magro L
%A Srour M
%J Bull Cancer
%V 0
%N 0
%D 2024 Apr 16
%M 38631984
%F 1.318
%R 10.1016/j.bulcan.2024.02.013
%X Chimeric antigen receptor T cell (CAR-T cell) therapy has become a standard-of-care for several hematological and a promising treatment for solid malignancies or for selected non-malignant autoimmune disorders. Hematological complications following this treatment are very common with the majority of patients experiencing at least one cytopenia after CAR-T cell injections. The management of these adverse events is not standardized and represents an area of active research and unmet clinical needs. This harmonization workshop, gathering a group of experts who analyzed this topic, has been conceived for the optimization of the management of patients presenting with post-CAR-T cell hematological toxicities. Based on the data present in the literature, these practical recommendations were made to harmonize the practices of Francophone centers involved in the management of these patients.