%0 Review
%T Translational Research and Health Equity: Gene Therapies for Sickle Cell Disease as a Case Study.
%A Majumder MA
%A Fasipe T
%J Ethics Hum Res
%V 46
%N 3
%D 2024 May-Jun
%M 38629220
暂无%R 10.1002/eahr.500211
%X In August of 2023, the National Academies of Science, Engineering, and Medicine published a timely report titled "Toward Equitable Innovation in Health and Medicine: A Framework." Here, we review some of the key contributions of the report, focusing on two dimensions of equity: input equity and deployment equity. We then use the example of new gene therapies to treat sickle cell disease (SCD) as a case study of input and deployment equity in translational research. The SCD case study illustrates the need for a kind of translational bioethics with deep understanding of lived experiences and clinical realities as well as a high degree of economic and policy sophistication.