%0 Case Reports
%T A Case of Chronic Eosinophilic Leukemia with CSF3R-Mutant Clone and Transformed to Secondary Acute Myeloid Leukemia.
%A Wu Y
%A Yang X
%J Clin Lab
%V 70
%N 4
%D 2024 Apr 1
%M 38623671
%F 1.053
%R 10.7754/Clin.Lab.2023.230924
%X <B>BACKGROUND: </B>Chronic eosinophilic leukemia (CEL) is a rare invasive disease characterized by non-specific cytogenetic abnormalities or elevated mother cells, poor prognosis, and a high risk of conversion to acute leukemia.<BR><B>METHODS: </B>We described the data of a patient with CEL-NOS.<BR><B>RESULTS: </B>This case is a CEL-NOS with four mutations in CSF3R-T618I, DNMT3A Q816, ASXL1, and IDH2.<BR><B>CONCLUSIONS: </B>The patient rapidly evolves into secondary acute myeloid leukemia (AML).