%0 Journal Article %T Development of an Artificial Intelligence Diagnostic System Using Linked Color Imaging for Barrett's Esophagus. %A Takeda T %A Asaoka D %A Ueyama H %A Abe D %A Suzuki M %A Inami Y %A Uemura Y %A Yamamoto M %A Iwano T %A Uchida R %A Utsunomiya H %A Oki S %A Suzuki N %A Ikeda A %A Akazawa Y %A Matsumoto K %A Ueda K %A Hojo M %A Nojiri S %A Tada T %A Nagahara A %J J Clin Med %V 13 %N 7 %D 2024 Mar 29 %M 38610762 %F 4.964 %R 10.3390/jcm13071990 %X Background: Barrett's esophagus and esophageal adenocarcinoma cases are increasing as gastroesophageal reflux disease increases. Using artificial intelligence (AI) and linked color imaging (LCI), our aim was to establish a method of diagnosis for short-segment Barrett's esophagus (SSBE). Methods: We retrospectively selected 624 consecutive patients in total at our hospital, treated between May 2017 and March 2020, who experienced an esophagogastroduodenoscopy with white light imaging (WLI) and LCI. Images were randomly chosen as data for learning from WLI: 542 (SSBE+/- 348/194) of 696 (SSBE+/- 444/252); and LCI: 643 (SSBE+/- 446/197) of 805 (SSBE+/- 543/262). Using a Vision Transformer (Vit-B/16-384) to diagnose SSBE, we established two AI systems for WLI and LCI. Finally, 126 WLI (SSBE+/- 77/49) and 137 LCI (SSBE+/- 81/56) images were used for verification purposes. The accuracy of six endoscopists in making diagnoses was compared to that of AI. Results: Study participants were 68.2 ± 12.3 years, M/F 330/294, SSBE+/- 409/215. The accuracy/sensitivity/specificity (%) of AI were 84.1/89.6/75.5 for WLI and 90.5/90.1/91.1/for LCI, and those of experts and trainees were 88.6/88.7/88.4, 85.7/87.0/83.7 for WLI and 93.4/92.6/94.6, 84.7/88.1/79.8 for LCI, respectively. Conclusions: Using AI to diagnose SSBE was similar in accuracy to using a specialist. Our finding may aid the diagnosis of SSBE in the clinic.